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Persistent morning vomiting with headache, unusual drowsiness, a squint or unsteadiness needs assessment today. These suggest raised pressure inside the skull. Also seek emergency care for a seizure, or for a child who cannot be roused normally.

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Brain tumours in children

The commonest solid tumours of childhood. Many are curable — some with surgery alone — and outcomes depend heavily on the treatment following an established protocol from the start.

Written for parents. Childhood brain tumours differ from adult ones in type, in behaviour and in outlook, and the difference is generally in your child's favour.

Commonest site
Back of the brain
The posterior fossa, near the fluid pathways
Early sign
Morning vomiting
With headache, often before anything else
Protocol matters
Enormously
Named protocols, followed completely
Time in India
6 weeks to 4 months
Surgery, and radiotherapy or chemotherapy after
The condition

What childhood brain tumours are

Children's brain tumours occur most often at the back of the brain, in the posterior fossa. Because that region sits beside the narrow channels through which fluid drains, these tumours frequently obstruct the flow and cause hydrocephalus — which is why raised-pressure symptoms often come before any weakness or clumsiness.

The common types differ entirely from adults. Medulloblastoma is a malignant tumour of the cerebellum that spreads through the fluid pathways and is treated with surgery, radiotherapy and chemotherapy. Pilocytic astrocytoma is a low-grade tumour that is frequently cured by complete surgical removal alone. Ependymoma arises from the lining of the fluid cavities. Brainstem gliomas vary enormously — some are treatable, and a particular type, diffuse midline glioma, currently is not.

Molecular subtyping has changed this field substantially. Medulloblastoma is now divided into groups with very different behaviour and outlook, and treatment intensity is adjusted accordingly — sparing some children treatment they do not need while intensifying it for those who do.

Radiotherapy is used cautiously in young children, particularly under three, because of its effect on the developing brain. Protocols are designed to delay or avoid it in the youngest patients where possible, using chemotherapy to buy time.

Symptoms

Symptoms and warning signs

Common signs in children
  • Headache, particularly on waking, with vomiting that then relieves it
  • Vomiting in the morning without other illness
  • Unsteadiness, clumsiness or a change in walking
  • A new squint or double vision
  • Head tilt held persistently to one side
  • Unusual drowsiness, irritability or personality change
  • In babies: enlarging head, bulging fontanelle, poor feeding, downward-fixed gaze
Warning signs of an emergency
  • Persistent morning vomiting with headache
  • Unusual drowsiness or difficulty waking
  • A seizure
  • Rapidly worsening unsteadiness or weakness
  • A new squint or downward-fixed gaze
  • In a shunted child, any recurrence of previous symptoms

Morning vomiting with headache in a child deserves a scan

The classic early pattern of a childhood brain tumour is headache on waking with vomiting that then relieves it, because pressure inside the skull rises overnight when lying flat. It is regularly attributed to migraine or a stomach upset for weeks or months. Add a new squint, a persistent head tilt, unsteadiness or a change in personality, and the case for imaging becomes strong. A child with this pattern should have a scan rather than another course of anti-sickness medicine.

Diagnosis

How it is diagnosed

Imaging first, then tissue, then molecular testing.

Initial tests

  • MRI of the brain with contrast — the primary investigation, ideally before any surgery
  • MRI of the whole spine — several childhood tumours spread through the fluid pathways, and this must be done before surgery where possible
  • Examination of the optic discs — swelling indicates raised pressure
  • Head circumference and growth chart in young children

The deciding tests

  • Tissue diagnosis with molecular subtyping — determines the group, the treatment intensity and the outlook
  • Lumbar puncture for tumour cells — after surgery, to complete staging where the tumour type spreads through fluid
  • Endocrine assessment — before and after treatment, particularly for tumours near the pituitary
  • Hearing and neuropsychological baseline — before chemotherapy and radiotherapy that can affect both

Send the spine MRI as well as the brain scan

For several childhood tumours, whether disease has spread through the fluid pathways to the spine changes the stage and therefore the treatment. That scan is ideally done before surgery, because blood and debris afterwards make it harder to interpret. Send the brain and spine MRI reports, your child's exact age and weight, and a description of the symptoms and when each began.

Options

Treatment options

Surgery is usually first, and what follows depends on the tumour type and your child's age.

Option one

Surgery

Maximal safe removal by a paediatric neurosurgeon. For low-grade tumours such as pilocytic astrocytoma, complete removal is frequently curative and no further treatment is needed. For malignant tumours, the extent of removal affects outcome and is followed by further treatment. Hydrocephalus is dealt with at the same time where present.

Usually appropriate whenAlmost all accessible tumours, both to treat and to obtain tissue for diagnosis and molecular subtyping.
Option two

Chemotherapy on protocol

Given according to an established protocol determined by tumour type, molecular group and age. In very young children it is also used to delay radiotherapy until the brain is more developed. Some phases can be given near home once the protocol is set, which we will map out for you.

Usually appropriate whenMalignant tumours, and in young children as a means of postponing radiotherapy.
Option three

Radiotherapy

Effective but used carefully in children because of effects on the developing brain, on growth and on hormones. Where it is needed, modern conformal techniques limit the dose to surrounding tissue. It requires daily attendance for several weeks and must be given in India.

Usually appropriate whenAccording to tumour type, stage and age — generally avoided or delayed under three years.
Alongside

Endocrine, hearing and developmental follow-up

Treatment can affect growth, puberty, thyroid function, hearing and learning. Long-term follow-up in all these areas is part of the treatment rather than an optional extra, and much of it can be arranged near your home once we set it out in writing.

Usually appropriate whenFor every child, continuing for years after treatment ends.
The decision

How the choice is made

Tumour type and molecular group

These determine both treatment and outlook, and they come from the tissue. Two children with the same tumour name can need different intensities of treatment.

Your child's age

Radiotherapy is avoided or delayed in the very young. Protocols are built around this and it shapes the whole sequence.

Whether the whole protocol can be completed

A long protocol begun and abandoned loses most of its benefit. We will give you the full duration and cost before anything starts.

Complex paediatric neurosurgery needs a paediatric neurosurgeon, a paediatric neuro intensive care unit and a paediatric oncology service in the same hospital. We verify all three, and it is often why we do not recommend the best-known name.

Urgency

How urgent is your case

Usually safe to plan travel
  • Child stable and alert
  • Investigations complete, planning surgery
  • Between chemotherapy cycles with no fever
  • Post-operative and recovering
Needs local assessment before travel
  • Drowsiness or difficulty waking
  • Persistent vomiting with headache
  • A seizure
  • Rapidly worsening unsteadiness
  • Fever during chemotherapy
  • Shunt symptoms in a shunted child

We will tell you which column you are in

Raised pressure inside a child's skull needs treating locally and urgently. Once it is relieved and the child is stable, planning definitive treatment here becomes safe.

Next step

What to send us

Photographs taken on your phone are fine. Reports in Arabic, Russian or Bengali are fine — we translate them ourselves.

Most useful

  • MRI of the brain with contrast
  • MRI of the whole spine if performed
  • Your child's exact age and weight
  • A description of symptoms and when each began

Also helpful

  • Pathology and molecular results if surgery has been done
  • Details of any treatment already given, with protocol name
  • Whether a shunt has been placed
  • Hearing test and endocrine results if available
Questions

Questions patients ask

Many are. Low-grade tumours such as pilocytic astrocytoma are frequently cured by complete surgical removal alone. Medulloblastoma is curable in a substantial proportion of children with full protocol treatment. Some, particularly diffuse midline glioma of the brainstem, currently are not, and we will tell you honestly which situation applies once we see the imaging and pathology.

Because several childhood brain tumours spread through the fluid that circulates around the brain and spinal cord. Whether that has happened changes the stage and therefore the treatment. The scan is best done before surgery, since blood and debris afterwards make it harder to interpret.

It is effective but carries real long-term effects on the developing brain, on growth and on hormones, which is why protocols avoid or delay it in children under three, using chemotherapy to buy time. Where it is necessary, modern conformal techniques reduce the dose to surrounding tissue. The risks and benefits should be discussed frankly for your child's specific age and tumour.

Surgery and recovery take around six weeks. If radiotherapy follows, add six to seven weeks in India because it is given daily. Chemotherapy protocols can extend over many months, and much of that can often be given near home once the protocol is written out. We will map the whole timeline before anything starts.

Many children do well, but treatment can affect learning, hearing, growth and hormone function, and follow-up in all these areas is part of the care rather than an afterthought. Younger children treated with radiotherapy are most at risk. Ask for a written long-term follow-up plan that your local doctors can carry out.

Tell us before treatment begins rather than partway through. A protocol started and abandoned loses most of its benefit, and an interrupted course is worse than a properly planned alternative. We will give you the full expected cost and duration upfront, and where the numbers do not work we will say so and help you consider what is achievable.

Contact

Send us your reports

Send the brain MRI and, if done, the spine MRI, along with your child's exact age and weight. Tell us when each symptom began.

Your reports go directly to our medical team. We do not share your records with hospitals until you tell us to.

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